Computational Models of cellular immunology

Moderator(s)

• 

  Mohammad Aminul Islam, PhD (he/him/his)

  Postdoctoral Associate
  University at Buffalo, The State University of New York
  Buffalo, New York, United States
• 

  Ashlee N. Ford Versypt, PhD (she/her/hers)

  Associate Professor
  Dept of Chemical & Biological Engineering, University at Buffalo, SUNY
  Buffalo, New York, United States

Presentations:

• 8:00 AM – 8:15 AM PDT

  Entropic Analysis of Antigen-Specific CDR3 Domains Identifies Essential Binding Motifs Shared by CDR3s with Different Antigen Specificities
  

  Presenting Author: Alexander Xu, PhD – Cedars Sinai Medical Center

  Co-Author: William Chour – Institute for Systems Biology

  Co-Author: Diana DeLucia – Fred Hutch

  Co-Author: Yapeng Su – Institute for Systems Biology

  Co-Author: Ana Pavlovitch-Bedzyk – Stanford University

  Co-Author: Rachel Ng – Institute for Systems Biology

  Co-Author: Yusuf Rasheed – Institute for Systems Biology

  Co-Author: Mark Davis – Stanford University

  Co-Author: John Lee – Fred Hutch

  Last Author: James Heath – Institute for Systems Biology
• 8:15 AM – 8:30 AM PDT

  Studying the mechanisms and predicting patient responses of B-cell acute lymphoblastic leukemia under CAR T-cell immunotherapy with a computational tool
  

  Presenting Author: Lunan Liu, MS (he/him/his) – New York University

  Co-Author: Chao Ma, PhD (he/him/his) – New York University Tandon School of Engineering

  Primary Investigator: Weiqiang Chen, PhD – New York University
• 8:30 AM – 8:45 AM PDT

  Tensor factorization maps dysregulation of immune signaling in breast cancer patients
  

  Presenting Author: Brian Orcutt-Jahns (he/him/his) – UCLA

  Last Author: Aaron Meyer – University of California, Los Angeles

  Co-Author: Peter Lee – City of Hope

  Co-Author: Andrei Rodin – City of Hope
• 8:45 AM – 9:00 AM PDT

  Systems Biology Analysis of T-cell Activation and Anti-tumor Immunity
  

  Presenting Author: Mohammad Reza Nikmaneshi, PhD (he/him/his) – Harvard Medical School and Massachusetts General Hospital

  Co-Author: Timothy P. Padera, PhD (he/him/his) – HARVARD MEDICAL SCHOOL

  Co-Author: James Baish, PhD (he/him/his) – Bucknell University

  Primary Investigator: Lance L. Munn – HARVARD MEDICAL SCHOOL
• 9:00 AM – 9:15 AM PDT

  A data-driven Boolean model explains memory subsets and evolution in CD8+ T cell exhaustion
  

  Presenting Author: Geena Ildefonso, PhD (she/her/hers) – University of Southern California

  Primary Investigator: Stacey Finley – Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, CA; Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA