Cancer Technologies

(F-203) Agent-based modeling of cancer cell migration and cytotoxic T cell response in glioblastoma

(F-207) Bone Marrow Vascular Microenvironment Combination RNAi Nanotherapy for Multiple Myeloma

(F-201) Determinants of NK cell cytotoxicity sensitivity in mouse models of breast cancer dormancy.

(F-206) Engineering a high throughput multilayer multicellular model of endometrial cancer for drug screening and drug delivery applications

(F-205) Engineering a co-cultured 3D in vitro model of cervical dysplasia for testing novel therapeutics

(F-204) Engineered Breast Cancer Models with Age-Mimetic ECM for Drug Screening

(H-288) Investigating the Effect of Increased Adipocyte Density on a 3D Human Breast Tumor Spheroid Model

(G-280) Utilizing Lipid Nanoparticles to Disrupt CD47-SIRPα Signaling Axis in Ovarian Cancer

(F-233) Interstitial Fluid Flow as a Predictor for Glioblastoma Invasion, Progression, and Recurrence.

(C-118) Differential Gene Expression of Patient Circulating Tumor Cells on Engineered Biomaterials

(F-232) Introducing mechanical stress into a reduced order model for breast cancer response to chemotherapy

(H-285) Scoping Review of Pre-clinical and Translational Studies on Macrophage Polarization in Nanoparticle-based Colorectal Cancer Immunotherapy

(H-281) Spatial Phospho-Proteomic Profiling of Cancer Tissues

(F-227) Glioblastoma culture in 3D hydrogel-based constructs highlights intertumoral heterogeneity and variable response to temozolomide

(F-226) In Vitro Dynamics of Pancreatic Cancer Organoids in 3D

(H-284) Three-Dimensional Fiber Anisotropy Analysis Using Multiple Orthogonal Projections

(C-119) CD44 Expression Drives Directed Migration in Ovarian Cancer Cells

(F-229) Label-free machine learning-based viability analysis of 3D tissue cultures

(H-282) Recapitulating Microglia Biophysical Dynamics in the Tissue-Engineered Glioblastoma Models to Study Tumor-Immune Crosstalk

(C-117) Characterization of Vascularized Tumor Explants for Personalized Medicine

(F-223) Engineering polymeric layer-by-layer nanoparticles for the targeted delivery of type I interferon in ovarian cancer

(C-116) Effects of Endothelial Cell tube formation on Glioblastoma Behavior during Tumor Growth

(H-283) Real-time Near-infrared Fluorescence Guided Protoporphyrin IX Imaging and Photodynamic Therapy for the Treatment of Glioblastoma

(D-128) Engineered 3D Tumor Immune Microenvironment On-a-Chip to Study the Interaction between T cells and Macrophages in Breast Cancer

(C-112) EAT: Electro-Antibacterial-Therapy To Target Intracellular Bacteria

(D-127) A Versatile, Reductionist Platform for Studying Integrin-EGFR Interactions in Colorectal Cancer

(D-129) Characterization of Lethal Pulsed Electric Fields for In Vitro Tumor Spheroids and Metastatic Invasion

(D-125) Antigen-specific Immunosuppression induced by Interactions Between Metabolic Glycan Labeled Erythrocytes and Macrophages

(F-230) Microengineering of Interstitial Fluid Pressure in Solid Tumor Microtissue Models

(F-228) FAK and AKT Signaling Regulate Mechanical Memory in Oral Squamous Cell Carcinoma

(D-123) A computational model of the relationship between intratumoral hyperthermia and fluid pressure

(F-225) Improving delivery of IL-12 through fusion with Elastin-like polypeptides

(D-121) Developing high-throughput pancreatic cancer in vitro model using DNA-directed patterning

(F-224) Modeling CSF1-dependent paracrine tumor-macrophage interactions in ovarian cancer using 3D microfluidics

(F-211) Immunogenicity of a Tumor Nano-Lysate Vaccine for Triple-Negative Breast Cancer

(D-122) Chimeric Invasion Assay (CIA) for Probing Collective Cancer Invasion in 3D Microenvironments

(F-212) Exosomal PD-L1-microRNA Pairs Detected by an Exo-PROS Liquid Biopsy Assay Predict Treatment Responses to Immune Checkpoint Inhibitor

(D-136) Collagen Mineralization Inhibits the Capacity of Macrophages to Stimulate Breast Cancer Cell Invasion

(H-287) Tumor immunological milieu after photonic therapy mediated by polyhydroxy fullerene in breast cancer

(D-126) Cancer cells as immune vampires

(F-210) Novel Drug Tomatidine Increases Chemosensitivity of Standard-of-care Gemcitabine In 3D Pancreatic Tumor Organoids

(D-124) Drug Delivery Application of Redox-Responsive and Dual-Targeted Folate-Conjugated Hyaluronic Acid-s-s-Gold nanoparticles For the Cancer Therapy

(H-286) Quantifying the Effects of Adipocyte-Secreted Factors on Breast Cancer Cell Behavior

(F-209) Large-Scale Nematic Organization of High-Grade Brain Tumors: Oncostreams, Topological Defects, and Their Functions

(F-217) Modeling Proliferation of Glioblastoma in Gelatin Maleimide Granular Hydrogels

(C-113) An Organotypic Model of Patient-derived Colorectal Tumor

(F-216) Impact of stroma remodeling on forces experienced by cancer cells and stromal cells

(C-114) Defining the contributions of N-linked, O-linked, and glycolipids to glycocalyx bulk and mechanically regulated migration in Glioblastoma Multiforme

(F-219) Metabolic Tagging and Targeted Modulation of Extracellular Vesicles

(F-215) FZD7-Targeted Nanoparticles to Enhance Chemosensitivity in Triple-Negative Breast Cancer

(C-115) A Single Conical Tube Device for Precision CAR-T Cells Manufacturing

(F-213) Modular, targeted microparticles for visualization of heterogeneous colorectal lesions

(F-220) Exploring the Impact of Extracellular Matrix Geometry on Tumor Evasion and T Cell Coevolution Through Stochastic Modeling

(F-221) Microvascularized Multiniche Tumor-On-a-Chip for Studying Ovarian Cancer Drug Resistance

(F-222) Integrin-Binding Peptide Cooperates with Soluble Transforming Growth Factor Beta 1 to Promote Metastasis in an Engineered Model of Prostate Cancer

(F-208) Optical metabolic signatures of extracellular vesicles from biofluids and ex vivo tissue in breast cancer using label-free multimodal multiphoton microscopy

(F-214) Monitoring immune dynamics in the tumor microenvironment via AND-gated protease sensors

(F-218) Overall survival is improved in a rodent glioma model with High-Frequency Irreversible Electroporation: Evaluating monotherapy and combinatorial therapy approaches.

(C-110) Increased Collagen Fiber Density Associated with Metastatic Ovarian Cancer Promotes Tumor Cell Adhesion

(G-246) Studying Responses of Multiple GBM Cell Lines to Extracellular Components

(C-111) Immuotherapy on Chip to Study T-Cell Transmigration toward Tumor

(G-247) Tumor Heterogeneity in Hypoxia-induced Metabolic Rewiring

(G-254) Studying the Crosstalk between MSCs and Osteotropic Cancer Cells

(C-109) Self-Adjuvanting α-Helical Polypeptide for Potent Neoantigen mRNA Vaccines

(G-248) Quantitatively Assessing the Effects of Extracellular Matrix Composition on Breast Cancer Phenotype

(G-253) Prompt and Sensitive Point-of-Care Diagnosis of Acute Promyelocytic Leukemia (APL) Using a Europium Lateral Flow Assay

(G-249) Validating in vitro models of breast to brain metastases across the blood-brain barrier

(G-250) Tuning Artificial Cytoskeleton of Cyborg Probiotics for Breast Cancer Gene Therapy

(G-251) Synergistic STING-activating and tumor-associated macrophage-targeting polymer-induced activation of innate immunity

(D-139) A Mathematical Model for Predicting the Spatio-temporal Response of Breast Cancer Cells treated with Doxorubicin

(G-252) Understanding the Impact of Antibody-Drug Conjugate Therapy on Immune Response

(G-243) Mapping spatiotemporal heterogeneities in collagen micro-mechanics under breast cancer cell driven remodeling

(G-244) Integration of Tumor Curette onto The Digit as a Means of Resection with Minimized Tissue Damage

(D-137) Diffusion Weighted Imaging for Improving the Diagnostic Performance of Breast MRI

(D-138) Development of a Three-dimensional Model on a Chip of Multifocal and Multicentric Breast Cancer for Studying Multiple-tumor Interaction and Progression

(C-108) Investigating the uptake of engineered bacterial membrane vesicles by cancer cells

(G-242) Matrix stiffness suppresses growth but induces genomic instability and variation in cancer spheroids

(D-130) Development of boronic acid-containing artificial alpha-helical cell-penetrating polypeptide-based proteasome inhibitor for cancer immunotherapy.

(G-245) Optimization of Localized Ablative Immunotherapy for Pancreatic Cancer Treatment

(D-140) Dynamics of lncRNA H19 Transcript Variant Relative to Triple Negative Breast Cancer

(C-105) Exploring the Role of Collagen Fiber Alignment Gradients as a Taxis Cue in Directing Cell Migration

(F-235) Identifying PDAC Diagnostic Biomarkers Utilizing Machine Learning Combined with Genome-Scale Metabolic Modeling

(C-107) Mechanistic Assessment of the Synergistic Role of Stromal and Immune Cells on Cancer Invasion using a Tumor-On-Chip Model

(F-236) Neutrophil Extracellular Traps sensing activates directional migration of Brain Metastatic Breast Tumors

(F-234) Location matters: Distinct patterns of macrophage activation and tumor promotion in bioengineered colorectal tumor models

(F-238) Personalized Drug Testing with Patient-derived Tumor Models – Experiments and Big Data Approach

(C-104) Targeting EZH2 in a Microfluidic Tumor-Spheroid Inducing Microgel System: A Novel Treatment for Triple-Negative Breast Cancer

(F-239) Near/Shortwave Infrared Fluorescent Imaging of Vascular Function in the Triple Negative Breast Cancer Tumor Microenvironment with BACH1 Attenuation

(D-131) Deep-learning triage of 3D pathology datasets for sensitive and time-efficient detection of esophageal neoplasia

(F-240) Glioblastoma Spheroid Growth, Infiltration, Motility, and Chemotherapeutic Responses in Single and Dual-Stiffness Hydrogels

(G-241) Highly sensitive circulating tumor cell (CTC) enumeration in multiple cancer types using a biomimetic and nanostructured capture surface

(D-132) A Personalized Prognostic System for Evaluating Chemoresistance and Chemotherapy-induced Invasion in Bladder Cancer

(D-133) Engineered basement membrane matrices to study morphogenesis and invasion of mammary epithelium

(C-106) Immunofluorescence-based Nuclear Morphometry Using Lamin Immunostaining and Fourier Analysis for Sensitive Detection of Nuclear Shape Abnormalities in Cancer Tissue

(F-237) Myosin-II inhibition under confined mitosis increases heritable chromosome loss through the suppression of multipolar divisions

(D-134) CRISPR-Generated Cell Model for Solitary Fibrous Tumors

(D-135) Development of a matrix metalloproteinase-9 activity based sensor to classify vestibular schwannomas

(D-128) Studying immunomechanics in a novel 3-D spheroid model of tumor-associated macrophages

(D-129) Spatial Multiomics Profiling of Angioimmunoblastic T-cell Lymphoma

(D-130) Using Radiomics Features Extracted from Multi-Parametric MRI to Help Predict Breast Cancer Response to Neoadjuvant Therapy

(E-196) Computational analysis of coadministration of antibody-drug conjugates to optimize payload delivery for solid tumor treatment

(E-197) Effect of PAX-FOXO1 fusion protein regulated by extracellular matrix on cancer cell phenotypes.

(E-198) Enhancing Immunotherapy via Chemokine-Driven Natural Killer Cells in 3D Melanoma Organ-on-a-Chip
Platform in Presence of Fibroblasts

(E-199) The Application of GNPs to Protect Nasopharynx Tubarial Salivary Glands During Radiotherapy

(E-200) Albumin-binding siRNA conjugates targeted against Mcl-1 effectively reduce metastatic tumor burden

(F-201) Development of a Mathematical Model Capable of Capturing IL-12 Pharmacokinetic Desensitization

(F-202) Differences in two optical signatures of metastasis among demographic groups

(F-202) In vivo mechanochemical dynamic cancer therapy using focused ultrasound-triggered mechanophores

(F-203) Establishing Orthotopic Murine Glioblastoma Model for Evaluating the Focused Ultrasound-Stimulated CAR-T Cell Therapy

(F-204) Mechanical Disruption by Focused Ultrasound Increase ERα Expression in Tamoxifen resistant Breast Cancer Cells

(F-205) Therapeutic potency testing of drug-loaded microparticles against glioblastoma using a perfusable tumor-on-chip platform

(F-206) Multiplexed, high-throughput drug and immune cell screening in 3D patient-derived tumoroid models

(F-207) Expansion of patient-derived tumoroids in a novel serum-free, Wnt-free, suspension culture system

(F-209) Ovarian Cancer Migration Regulated by Vascular Senescence

(F-210) Autofluorescence lifetime imaging reveals the role of metabolism in cancer immunosuppressive response to interferon gamma

(F-211) Hyaluronic Acid Synthase overexpression promotes the expansion of breast epithelial spheroids

(F-212) In vitro Assessment of Bacterial Swimming in Simulated Breast Cancer Microenvironments 

(F-213) Discovery of a highly potent oncolytic peptide via structure-activity relationship analysis of CKS1 mutants

(F-214) Computational Model for Multidimensional 3-phase Cancer Cell Migration Under Osmotic Pressure

(F-215) Development of in Silico Model of Pancreatic Tissue

(F-217) Color Space Based Segmentation Method For Spatial Analysis of Cytotoxic T Lymphocytes In Colorectal Cancer Patients

(F-218) A biomaterial model to study matrix remodeling and invasion of drug-resistant glioblastoma

(F-219) An Evaluation of Photointiators and Viability Assays on Panc-1 Pancreatic Cancer Cells

(F-220) High Grade Serous Ovarian Cancer Cells Respond to Fluid Shear Stress Through MUCIN15 to Adopt EMT Phenotypes

(F-221) Manipulation of Burst Pressure within FRESH Vascularization

(F-222) Analyzing the Targeting and Stimuli-Responsive Components of a Multi-Functional Peptide to Induce Gene Knockdown in Glioblastoma Cells in vitro.

(F-223) Examining the Apoptotic Mechanism of Piezo1 Activation and TRAIL Sensitization in Glioblastoma Cells

(F-224) A peptide derived from IL-10 exhibits potential anticancer activity and can facilitate cell targeting of gold nanoparticles loaded with anticancer therapeutics

(F-225) HER2+ breast cancer drives the in-vitro expression of Tumor-Associated Macrophage Markers in the Tumor Microenvironment

(F-226) Hypertrophic expansion of adipocytes in breast cancer

(F-227) Downregulation of TFAM enhances the sensitivity of Human Papillomavirus-negative head and neck cancer to radiation and immunotherapy

(F-228) The Effects of Manganese Oxide Nanoparticle Concentrations on Magnetic Resonance Imaging (MRI) Signal Quenching in Breast Cancer Cells

(F-229) Optimizing Folate-Peptide Intermediate for Universal Chimeric Antigen Receptor T-Cell Therapy

(F-230) OPEN-SOURCE ROBOTIC PLATFORM FOR AUTOMATED MICROMANIPULATION OF LIVE MICROTISSUES

(F-231) Comprehensive Investigation of INSPIRE Therapy: Mechanisms, Efficacy, and Treatment Optimization for Large Inoperable Tumors

(F-232) Elucidation of the mechanism of cancer cell death caused by oncolytic peptide CKS1

(F-233) Influence of collagen alignment on E-cadherin expression and cell metabolism in pancreatic ductal adenocarcinoma

(F-234) Design and Application of pDA Treatment Method for Polylactide Fibers to Enhance Cell Separation of MCF-7 Cells

(F-236) Investigating of the effects of pancreatic tumor-adipose cell cross talk in a 2D in vitro model

(F-237) In vitro characterization of an enzyme-cleavable tandem peptide for siRNA delivery to ovarian cancer cells

(F-238) Agent-based Modeling of Cell Interactions to Predict Metastasis in Pancreatic Cancer

(F-239) Microwells for Uniform Growth of Cancer Spheroids and Organoids

(G-241) Manipulation of Burst Pressure within FRESH Vascularization

(G-242) Establishment of a series of lung-metastatic breast cancer lines using a fully immunocompetent mouse model

(G-255) Spheroid Tumor Models for Assessing Peptide-Induced Immunogenic Cell Death

(G-256) Confinement drives memory via mitochondrial localization and vinculin-containing focal adhesion formation

(G-257) Sorting chemotherapeutic-resistant cells from recently resected glioblastoma tumors

(H-289) Exosomal Thomsen-Friedenreich Glycoantigen as a New Biomarker for Cancer Liquid Biopsy

(M-502) Increased Efficacy of a Melanoma mRNA-LNP Vaccine Containing Co-stimulatory Molecules

(M-514) Engineering a mRNA-LNP Vaccine for Efficacy in a Pancreatic Mouse Model