Postdoctoral research fellow
Harvard Medical School and Massachusetts General Hospital
Mohammadreza Nikmaneshi,PhD,Research Fellow,Harvard Medical School/Mass General Hospital
Dr. Mohammadreza Nikmaneshi is a dedicated Postdoctoral Research Fellow at Harvard Medical School and Massachusetts General Hospital, with a profound focus on disease modeling, particularly in the context of cancer research. His research endeavors revolve around recreating the intricate physiological and morphological aspects of diseases to enhance treatment strategies.
Armed with a unique background that spans both engineering and biology, Dr. Nikmaneshi excels in the development of sophisticated systems biology models. These models serve as invaluable tools for unraveling the complexities inherent to biological systems.
Dr. Nikmaneshi earned his doctoral degree in mechanical engineering, concurrently serving as a Research Assistant in Steele Laboratories at Massachusetts General Hospital and Harvard Medical School. During his master's studies, he delved into the modeling of dynamic processes within living cells. Subsequently, during his doctoral journey, his research focus expanded to encompass the multiscale modeling of cancer, spanning molecular, cellular, and tissue levels. This pioneering work was aimed at predicting cancer responses to various treatments and optimizing therapeutic interventions.
In his current role as a Postdoctoral Research Fellow, Dr. Nikmaneshi is at the forefront of a multidisciplinary research project. His work encompasses a wide spectrum of investigations, including ex vivo and computational modeling of vascularized solid cancers, with a specific emphasis on quantifying their responses to therapy. Furthermore, he explores the activation of the immune system and its intricate interactions with cancer through the lens of pharmacokinetics and pharmacodynamics (PKPD) modeling. Additionally, Dr. Nikmaneshi delves into the crucial realm of hemorheology and coagulation issues, with a keen focus on their impact on cancer patients.
Dr. Nikmaneshi's commitment to pioneering research at the intersection of engineering and biology promises to make significant contributions to our understanding of disease processes, ultimately advancing the field of cancer research and therapeutic interventions.