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Research Assistant Professor
University of Southern California
Dr. Longwei Liu is an Assistant Professor of Research at the Alfred E. Mann Department of Biomedical Engineering at USC Viterbi School of Engineering. The current research focus of Dr. Liu is to develop tools to better understand and control intracellular signaling, with a specific interest in immune-tumor cell interactions. Specifically, he develop genetically-encoded biosensors based on FRET or single fluorescent protein using a directed evolution approach and apply these biosensors to visualize molecular signals in live cells with high spatiotemporal resolution and for drug testing. With the guidance of these new signaling insights, he also develop novel clinically-compatible heat and ultrasound-responsive CAR-T cells for efficient immune therapy targeting solid tumors.