Postdoctoral Associate
Weill Cornell Medical College
Duc-Huy T. Nguyen PhD
Postdoctoral Associate
Weill Cornell Medical College, New York.
I am currently a postdoctoral associate in Dr. Robert Schwartz laboratory at Weill Cornell Medical College (WCMC), New York City, New York. Prior to working in Dr. Robert Schwartz's laboratory, I completed my PhD training as a chemical and biomolecular engineer in Dr. Christopher Chen's laboratory at the University of Pennsylvania. During my PhD, I engineered 3D angiogenic microfluidic models to study blood vessel formation. Subsequently, I was trained in vascular biology in Dr. Shahin Rafii’s laboratory at WCMC. During my work in Dr. Rafii’s laboratory, I employed bioinformatics and transcriptional programming to engineer endothelial cells with a unique capacity to form stable and robust vessel network in vitro and in vivo. Currently, as a postdoctoral fellow in Dr. Schwartz’s laboratory, I specialized in engineering 3D vascularized liver on a chip models to interrogate the cellular interactions between hepatocytes and the liver non-parenchymal cells (liver sinusoidal endothelial cells and hepatic stellate cells). My goal is to utilize 3D biomimetic vascularized liver on a chip model to not only investigate the molecular cross-talks between different liver cells, but also to model liver diseases such as non-alcoholic fatty liver disease. As many chronic liver diseases become a global burden, liver transplantation therapies to treat liver diseases do not meet the current translational needs due to the shortage of organs and donors. As such, I aim to utilize my expertise in vascular tissue engineering to engineer vascularized liver tissue for liver transplantation as an alternative treatment for chronic liver diseases.