Graduate Research Student
Texas A&M University
Yi-Tsang Lee obtained his Master of Biotechnology degree from Texas A&M University, where he also received a certificate in Business at Texas May Business School. He completed his Bachelor of Science in Nutrition at China Medical University (Taiwan) and received a Certificate of Chinese Medicine Program.
Lee is now a Ph.D. candidate at Texas A&M University's Institute of Biosciences and Technology. With background in synthetic biology, optogenetics, and chemogenetics, Lee has made impressive contributions to these fields through his creative research. He has developed expertise in cell culture, molecular biology, biochemistry, animal studies, RNA-seq data analysis, ChIP-seq, qPCR, western blot, virus transduction, and molecular cloning.
Lee's research has resulted in several high-impact publications, including a paper in Science Advances where he served as a first author. In this article, Lee and his colleagues described how light-activated macromolecular phase separation modulates gene transcription by reconfiguring chromatin interactions. He also published additional paper in premier journals such as Nature Communications, Advanced Science, Seminars in Cancer Biology, Biochemical Journal, and Stem Cells.
Lee has presented his research at various professional conferences, including the FASEB Calcium and Cell Function Conference and the Gordon Research Conference on Calcium Signaling. He has given oral and poster presentations on topics such as optogenetic control of calcium influx in mammalian cells and circularly permuted LOV2 as a modular photoswitch for optogenetic engineering.