Modeling cardiac fibrosis: exogenous extracellular matrix impairs 3D cardiac tissue formation

Friday, October 13, 2023

8:45 AM – 9:00 AM PDT

Location: 342 (Center, Level 3)

Presenting Author(s)

Natalie Pachter, BE (she/her/hers)

PhD candidate
Binghamton University
Binghamton, New York, United States

Co-Author(s)

KA

Kristen Allen

Binghamton University, United States

Primary Investigator(s)

TH

Tracy Hookway, PhD (she/her/hers)

Assistant Professor
Binghamton University, New York, United States

Few treatments exist for cardiac fibrosis, which is a stiffening of the heart muscle that prevents the heart from beating properly. Here, we create an in vitro 3D cardiac tissue model which combines cardiomyocytes, cardiac fibroblasts, and extracellular matrix proteins to better understand the mechanisms of cardiac fibrosis and develop new treatments.