(J-386) A Wearable, Multimodal Breath Sensor for Diagnosis and Monitoring of Chronic Liver and Kidney Diseases.

Breath ammonia is an important biomarker for patients with chronic kidney disease (CKD) and chronic liver disease (CLD). However, existing breath ammonia sensors fail to compensate for the complications associated with taking a breath sample. Here, we present a multimodal breath sensing system that integrates an ammonia sensor, humidity sensor, and a breath dynamics sensor. On-body tests highlight the operational simplicity and practicality of the system for noninvasively tracing essential biomarkers, suggesting its promising potential to capture early warning signs of organ dysfunction for patients with CKD and CLD.